Childbearing in coagulation disorders: Genetics (F2 and F5)
Congenital clotting disorders can be identified by changes in certain genes that affect blood clotting. These genetic mutations can increase the risk of thrombosis during pregnancy.
The most common hereditary thrombophilias are factor V Leiden and factor II (prothrombin), affecting between 3% and 11% of the population.
Individuals with a genetic predisposition to these clotting disorders may be at increased risk for developing deep vein thrombosis during pregnancy due to the increase in estrogens. In addition, such mutations may lead to an increased risk of recurrent miscarriage and pregnancy complications.
A predisposition to thrombophilia due to genetic factors can be determined by testing the genes involved in the blood clotting process (factor II, factor V). The mutations detected are subsequently analyzed.
Depending on the results, a close monitoring program or preventive measures, such as administration of low-dose aspirin, may be initiated.
Genes studied: F2, F5
Grisons women become mothers late
Even 50 years ago, Swiss women were older than the European average when their first child was born. However, there are also differences between the cantons. Text: Romina Kranz (Editor, Südostschweiz, January 30, 2024) In the last 50...
Read more
Iron deficiency due to menstruation
Dr. med. Lydia Unger-Hunt conducts the interview with Prof. Dr. med. Christian Breymann, gynaecologist from Zurich, and general practitioner Dr. med. Urs Hürlimann, general practitioner from Hünenberg. The interview focuses on the roles of gynecologists and general practitioners in...
Read moreTreatment of heavy bleeding disorders by sclerosing the uterine lining (NovaSure method)
Heavy menstrual bleeding (menorrhagia, hypermenorrhea) is a common problem in women, especially after childbirth or after the age of 40. This excessive bleeding can lead to missed work and a feeling of weakness. Although hormone treatments or hormonal IUDs exist to regulate bleeding, there are...
Read more