Childbearing in coagulation disorders: Genetics (F2 and F5)

GYN & PERINATAL ZURICH > Childbearing in coagulation disorders: Genetics (F2 and F5)

Congenital clotting disorders can be identified by changes in certain genes that affect blood clotting. These genetic mutations can increase the risk of thrombosis during pregnancy.

The most common hereditary thrombophilias are factor V Leiden and factor II (prothrombin), affecting between 3% and 11% of the population.

Individuals with a genetic predisposition to these clotting disorders may be at increased risk for developing deep vein thrombosis during pregnancy due to the increase in estrogens. In addition, such mutations may lead to an increased risk of recurrent miscarriage and pregnancy complications.

A predisposition to thrombophilia due to genetic factors can be determined by testing the genes involved in the blood clotting process (factor II, factor V). The mutations detected are subsequently analyzed.

Depending on the results, a close monitoring program or preventive measures, such as administration of low-dose aspirin, may be initiated.

Genes studied: F2, F5

Perinatal stem cell research: Prof. Breymann in conversation with Famido.ch

March 20, 2024

This episode is about the fascinating world of stem cell storage from the placenta and umbilical cord. Prof. Breymann, a recognized expert in the field of perinatal stem cell research and pregnancy, discusses the key aspects of this topic with Ms. Isabell Ziegler from famido.ch. In doing so...

Read more

First Children's Runway Congress at THE CIRCLE at Zurich Airport (May 25, 2024)

March 1, 2024

The new "Kinderstartbahn" platform brings together experts from pediatrics and related fields with the common goal of giving children the best possible start in life. Dates: Saturday, May 25, 2024 Location: Circle Convention Center at Zurich Airport. Expert audience and continuing education points Around...

Read more

Grisons women become mothers late

January 30, 2024

Even 50 years ago, Swiss women were older than the European average when their first child was born. However, there are also differences between the cantons. Text: Romina Kranz (Editor, Südostschweiz, January 30, 2024) In the last 50...

Read more