GYN & PERINATAL ZURICH > Conservative Management of an Abnormal Preeclampsia Index: Two Case Reports Incorporating sFlt-1/PlGF Dynamics

Conservative Management in Cases of an Abnormal Preeclampsia Index: Two Case Studies Incorporating sFlt-1/PlGF Dynamics

The sFlt-1/PlGF ratio is an important indicator for assessing the risk of preeclampsia. However, a single elevated reading does not automatically mean that an immediate delivery is necessary. The decisive factor is always the overall picture of the mother and baby—including symptoms, blood pressure, lab results, the trend of the ratio, and fetal monitoring.

Two case studies show that, in a stable situation, a closely monitored “wait-and-see” approach may be possible. If the test results trend favorably and both the mother and child remain stable, unnecessary interventions can be avoided. If, on the other hand, the clinical condition worsens and the test results rise significantly again, a rapid delivery may become necessary.

Conclusion: It is not a single lab result that determines the outcome, but rather the course of the pregnancy and the overall situation. Careful, close monitoring allows for a safe, individually tailored decision for both mother and child.

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